New Molecular Biology Findings from Technical University Discussed (Posttranscriptional regulatory networks: from expression profiling to integrative...

Life Science Weekly |


New Molecular Biology Findings from Technical University Discussed (Posttranscriptional regulatory networks: from expression profiling to integrative analysis of mRNA and microRNA data) By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Life Science Research. According to news reporting originating in Freising, Germany, by NewsRx journalists, research stated, "Protein coding RNAs are posttranscriptionally regulated by microRNAs, a class of small noncoding RNAs. Insights in messenger RNA (mRNA) and microRNA (miRNA) regulatory interactions facilitate the understanding of fine-tuning of gene expression and might allow better estimation of protein synthesis." The news reporters obtained a quote from the research from Technical University, "However, in silico predictions of mRNA-microRNA interactions do not take into account the specific transcriptomic status of the biological system and are biased by false positives. One possible solution to predict rather reliable mRNA-miRNA relations in the specific biological context is to integrate real mRNA and miRNA transcriptomic data as well as in silico target predictions." According to the news reporters, the research concluded: "This chapter addresses the workflow and methods one can apply for expression profiling and the integrative analysis of mRNA and miRNA data, as well as how to analyze and interpret results, and how to build up models of posttranscriptional regulatory networks." For more information on this research see: Posttranscriptional regulatory networks: from expression profiling to integrative analysis of mRNA and microRNA data. Methods In Molecular Biology, 2014;1160():165-88 (see also Life Science Research). Our news correspondents report that additional information may be obtained by contacting S.U. Meyer, Physiology Weihenstephan, ZIEL Research Center for Nutrition and Food Sciences, Technische Universitat Munchen, Weihenstephaner Berg 3, D-85354, Freising, Germany. Additional authors for this research include K. Stoecker, S. Sass, F.J. Theis and M.W Pfaffl. Keywords for this news article include: Europe, Germany, Freising, Life Science Research. Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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