Lexaria Bioscience Corp

(LXX:CNX)

By |

Lexaria Bioscience Corp. (CSE:LXX; OTCQX:LXRP) has developed and out-licenses its disruptive and cost-effective DehydraTECH™ technology that promotes healthier administration methods, lower overall dosing and higher effectiveness of ingestible drugs and other beneficial molecules.

Many vitamins, drugs, supplements and other beneficial molecules are lipophilic (i.e. fat soluble) and difficult for the human gastrointestinal system to efficiently and effectively absorb. DehydraTECH™ greatly improves the body’s ability to absorb these substances so their benefits can be received more quickly and pleasantly.

Lexaria has multiple patents issued or pending in over 40 countries around the world.

Technology Overview

Lexaria has developed and commercialized a patented and cost-effective delivery technology (DehydraTECH™) that has been both laboratory and market proven to enhance the performance of beneficial compounds in ingestible products across four categories:

  • Taste
  • Smell
  • Speed of action
  • Bioabsorption & bioavailability

Lexaria’s technology is easily applied through incorporation of an intermediate step in the formulation and manufacturing of existing or new ingestible products. This step involves mixing the beneficial compound of interest as a delivery “payload” together with certain fatty acids, infusing the mixture into a substrate material, and then using controlled dehydration synthesis processing to conjugate the payload and fatty acids together at a molecular level before integrating the newly-combined molecules into production.

A Versatile Solution to Improve Bioabsorption, Taste, and Efficacy

Compounds processed using Lexaria’s DehydraTECH™ system become masked to oral and olfactory receptors, rendering them essentially flavorless and odorless. As such, DehydraTECH™ formulations do not require unwanted sweeteners or chemical masking agents for flavor and odor blocking. This allows manufacturers to create low-sugar products with fewer calories, while also avoiding the use of excessive artificial sweeteners.

After being swallowed, the fatty acids are believed to protect the conjugated payload from hostile stomach conditions and expedite its transit to the small intestine where nutrient bioabsorption occurs. Once in the small intestine, the fatty acids are believed to enable rapid and more significant permeation of the intestinal wall for the conjugated payload, then transport it to the systemic circulation by one of two pathways depending on the type of fatty acid(s) chosen for each specific formulation:

1. Hepatic Transport

In cases where liver metabolism is desirable for biotransformation of the payload before access to the general circulation, Lexaria’s methodology uses medium chain fatty acids for formulation purposes since they are absorbed via the portal vein and transported to the liver for processing prior to entering the general circulation. This would be applicable, for instance, with prodrug compounds that rely on metabolism by liver enzymes to become pharmacologically active within the human body.

2. Lymphatic Transport

Conversely, in cases where faster onset of action and/or maximizing action of the originally formulated payload without biotransformation is desirable, Lexaria’s methodology uses long chain fatty acids, which are absorbed via the lymphatic lacteals thereby diverting away from the liver and entering the general circulation very quickly. For payloads that deliver pain relief or meet other immediate needs, this rapidity of onset is a vital benefit.

DehydraTECH™ formulations may also permit formulation with a combination of long and medium chain fatty acids in the same preparation for purposes of engineering products with both fast and sustained release profiles. Such timed-release formulations can be sought to deliver beneficial payloads both quickly, as well as over a sustained duration for several hours.

DehydraTECH™ formulations have been shown through in vitro and in vivo studies to increase intestinal bioabsorption of bioactive compounds by as much as 5-10X and demonstrate effectiveness in as little as 15 minutes after administration (see: Research). Lexaria’s DehydraTECH™ process has the added benefit of being very cost-effective to implement; requiring micro quantities of fatty acid ingredient incorporation into food, beverage, and capsule products at a fraction of a penny per serving, together with the use of processing equipment that is readily found in most commercial kitchen/production facilities and is highly scalable.

Click here for more information

Management

Mr. Chris Bunka
Chairman of the Board & CEO

Chris has been Chairman of the Board and CEO since 2006 and was primarily responsible for the corporate pivot from older business activities to bioscience.

Chris is a serial entrepreneur and has been involved in several private and public companies since the late 1980’s. He was well known for more than a decade as a part-time business commentator in print and radio, as well as an author. He has extensive experience in the capital markets, corporate governance, project acquisition and corporate finance. He is a named inventor on some of Lexaria’s pending patents.


Mr. John Docherty
President and Director

John became President of Lexaria in the Spring of 2015 and joined its board of directors a year later. Mr. Docherty was former President and Chief Operating officer of Helix BioPharma Corp. (TSX: HBP), where he led the company’s pharmaceutical development programs for its plant and recombinantly derived therapeutic protein product candidates.

Mr. Docherty is a senior operations and management executive with over 20 years of experience in the pharmaceutical and biopharmaceutical sectors. He has worked with large multinational companies, as well as emerging private and publicly-traded start-ups. At Helix, Mr. Docherty was also instrumental in the areas of investor and stakeholder relations, capital raising, capital markets development, strategic partnering, regulatory authority interactions and media relations, and he also served as a management member of its board of directors. Prior to this, Mr. Docherty was president and a board member of PharmaDerm Laboratories Ltd., a Canadian drug delivery company that developed unique microencapsulation formulation technologies for use with a range of active compounds.

Mr. Docherty has also held positions with companies such as Astra Pharma Inc., Nu-Pharm Inc. and PriceWaterhouseCoopers’ former global pharmaceutical industry consulting practice. He is a named inventor on issued and pending patents and he has a M.Sc. in Pharmacology and a B.Sc. in Toxicology from the University of Toronto.


Mr. Allan Spissinger
Chief Financial Officer & Corporate Secretary

Prior to concentrating on finance and accounting, Mr. Spissinger worked within the Informational Technologies (IT) sector for over a decade; specializing in corporate IT infrastructure and software development projects. Mr. Spissinger joined the audit and assurance department at PricewaterhouseCoopers (PwC) where he obtained his Chartered Professional Accountant (CPA) designation focusing on financial reporting and Sarbanes-Oxley (SOX) compliance in the following sectors: resources, manufacturing and technologies. Mr. Spissinger joined Lexaria in September 2014 as a corporate controller. His positive mentorship, excellent communication and extensive leadership skills have enabled him to successfully manage a variety of private businesses for over 20 years.


Mr. Alex Blanchar
Manager Corporate Communications and Investor Relations

Alex entered the brokerage business in 1996 and enjoyed a 20 year career as an investment advisor with a focus on micro-cap equities and public venture capital. Over the course of his career, he was involved in advising and financing numerous public and private companies and developed a large network of retail and institutional clients in Canada, Europe and the United States. Alex holds a Bachelor of Arts degree which he received from UBC in 1992.


Additional Information


Lexaria Bioscience Corp

Profile

Lexaria Bioscience Corp. (CSE:LXX; OTCQX:LXRP) has developed and out-licenses its disruptive and cost-effective DehydraTECH™ technology that promotes healthier administration methods, lower overall dosing and higher effectiveness of ingestible drugs and other beneficial molecules.

Contact Information

Website: www.lexariabioscience.com
Email: info@lexariabioscience.com
Main Phone: +1 250 765-6424
Address: 156 Valleyview Road
State: BC
City / Town: Kelowna
Country: CAN
Postal Code: V1X 3M4

Issuer Information

Exchange: CNQ
CEO: Christopher Bunka
Issuer Type: CS - Common Stock
Sector/Industry: Consumer Defensive
NAICS: All Other Miscel
$ 1.73 $ 0.16 (10.19%)
Last Price 1.73 Change $ 0.16 Change % 10.19 Tick N/A
Bid 1.72 Bid Size 1,000.00 Ask 1.73 Ask Size 900.00
Open 1.51 High 1.80 Low 1.51 Prev Close 1.57
Last Trade Volume 374,291 52 Wk Hi 3.23 52 Wk Low 0.35
Market Cap 124.2 mi Ex-Div Date N/A Div Rate N/A Yield N/A
Shares 71,772,305.00 EPS (TTM) -0.06 PE Ratio N/A Exchange CSE