Study Data from Wuhan University Update Knowledge of Drug Development (Natural products from mangrove actinomycetes)

By a News Reporter-Staff News Editor at Drug Week — Data detailed on Drugs and Therapies have been presented. According to news reporting from Wuhan, People’s Republic of China, by NewsRx journalists, research stated, “Mangroves are woody plants located in tropical and subtropical intertidal coastal regions. The mangrove ecosystem is becoming a hot spot for natural product discovery and bioactivity survey.”
The news correspondents obtained a quote from the research from Wuhan University, “Diverse mangrove actinomycetes as promising and productive sources are worth being explored and uncovered. At the time of writing, we report 73 novel compounds and 49 known compounds isolated from mangrove actinomycetes including alkaloids, benzene derivatives, cyclopentenone derivatives, dilactones, macrolides, 2-pyranones and sesquiterpenes. Attractive structures such as salinosporamides, xiamycins and novel indolocarbazoles are highlighted. Many exciting compounds have been proven as potential new antibiotics, antitumor and antiviral agents, anti-fibrotic agents and antioxidants. Furthermore, some of their biosynthetic pathways have also been revealed.”
According to the news reporters, the research concluded: “This review is an attempt to consolidate and summarize the past and the latest studies on mangrove actinomycetes natural product discovery and to draw attention to their immense potential as novel and bioactive compounds for marine drugs discovery.”
For more information on this research see: Natural products from mangrove actinomycetes. Marine Drugs, 2014;12(5):2590-613 (see also Drugs and Therapies).
Our news journalists report that additional information may be obtained by contacting D.B. Xu, Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, People’s Republic of China. Additional authors for this research include W.W. Ye, Y. Han, Z.X. Deng and K. Hong.
Keywords for this news article include: Asia, Wuhan, Drugs and Therapies, People’s Republic of China.
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