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Coronavirus

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Moderna Inc’s experimental vaccine was 94.5% effective in preventing COVID-19 based on interim data from a late-stage trial, the company said on Monday, becoming the second U.S. drugmaker to report results that far exceed expectations.

Together with Pfizer Inc’s vaccine, which is also more than 90% effective, and pending more safety data and regulatory review, the United States could have two vaccines authorized for emergency use in December with as many as 60 million doses of vaccine available this year.

Next year, the U.S. government could have access to more than 1 billion doses just from the two vaccine makers, more than needed for the country’s 330 million residents.


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More than 11 million cases of the coronavirus have now been reported in the United States, with the most recent million coming in less than a week.

Johns Hopkins University’s coronavirus tracker reached 11 million on Sunday. It had topped 10 million cases on Nov. 9.

It took 300 days for the U.S. to hit the 11 million mark since the first case was diagnosed in Washington state on Jan. 20.

COVID-19 is spreading more rapidly across the U.S. than it has at any time since the pandemic started. Deaths are also on the rise, though not at the record high numbers reached in the spring. The seven-day rolling average for daily new deaths was more than 1,080 as of Saturday, more than 30% higher than it was two weeks earlier.


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The governors of Oregon and New Mexico ordered near-lockdowns Friday in the most aggressive response yet to the latest wave of coronavirus infections shattering records across the U.S., even as many of their counterparts in other states show little appetite for reimposing the hard-line restrictions of last spring.

“We are in a life-or-death situation, and if we don’t act right now, we cannot preserve the lives, we can’t keep saving lives, and we will absolutely crush our current health care system and infrastructure,” Democratic Gov. Michelle Lujan Grisham of New Mexico said in imposing a two-week stay-at-home order.


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Antiviral remdesivir should not be used as a routine treatment for COVID-19 patients in critical care wards, the head of one of the world's top bodies representing intensive care doctors said, in a blow to the drug developed by U.S. firm Gilead.

Remdesivir, also known as Veklury, and steroid dexamethasone are the only drugs authorized to treat COVID-19 patients across the world. But the largest study on remdesivir’s efficacy, run by the World Health Organization (WHO), showed on Oct. 15 it had little or no impact, contradicting previous trials.


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Temperature and COVID-19 symptom checks like the ones used at schools and doctor’s offices have again proved inadequate for spotting coronavirus infections and preventing outbreaks.

A study of Marine recruits found that despite these measures and strict quarantines before they started training, the recruits spread the virus to others even though hardly any of them had symptoms. None of the infections were caught through symptom screening.

The study, published Wednesday in the New England Journal of Medicine, has implications for colleges, prisons, meatpacking plants and other places that rely on this sort of screening to detect infections and prevent outbreaks.


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Texas on Wednesday became the first state with more than 1 million confirmed COVID-19 cases, and California closed in on that mark as a surge of coronavirus infections engulfs the country from coast to coast.

In New York, Gov. Andrew Cuomo said all restaurants, bars and gyms statewide will have to close at 10 p.m. starting Friday, a major retreat in a corner of the U.S. that had seemingly brought the virus largely under control months ago. He also barred private gatherings of more than 10 people.


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California and several states across the U.S. Midwest tightened restrictions on residents on Tuesday as the nation’s top infectious disease specialist called on Americans to remain vigilant until a vaccine can be approved and distributed.

The new clampdowns were announced as the number of COVID-19 infections surged again in the United States with the onset of colder weather, straining hospitals and medical resources in some cities.

“There’s a real thing called COVID-19 fatigue, that’s understandable,” Dr. Anthony Fauci, a member of the White House coronavirus task force, told CNN in an interview. “But hang in there a bit longer, do the things you need to do and we’ll be OK.”


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The U.S. Food and Drug Administration on Monday authorized emergency use of Eli Lilly and Co’s experimental COVID-19 antibody treatment for non-hospitalized patients older than 65 or who have certain chronic medical conditions.

The FDA said its emergency use authorization (EUA) was based on clinical trials showing that the treatment, bamlanivimab, reduced the need for hospitalization or emergency room visits in COVID-19 patients at high risk of disease progression.

It can now be used for treating mild-to-moderate COVID-19 in adults and pediatric patients over the age of 12, the FDA said.


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Pfizer Inc said on Monday its experimental COVID-19 vaccine was more than 90% effective, a major victory in the fight against a pandemic that has killed more than a million people, battered the world's economy and upended daily life.

Pfizer and German partner BioNTech SE are the first drugmakers to release successful data from a large-scale clinical trial of a coronavirus vaccine. The companies said they have so far found no serious safety concerns and expect to seek U.S. authorization this month for emergency use of the vaccine.


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Despite Trump administration efforts to erect a protective shield around nursing homes, coronavirus cases are surging within facilities in states hard hit by the latest onslaught of COVID-19.

An analysis of federal data from 20 states for The Associated Press finds that new weekly cases among residents rose nearly four-fold from the end of May to late October, from 1,083 to 4,274. Resident deaths more than doubled, from 318 a week to 699, according to the study by University of Chicago health researchers Rebecca Gorges and Tamara Konetzka.