Critical Outcome Technologies Adds First European Patent to Growing Intellectual Property Protection for COTI-2

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LONDON, ON--(May 11, 2015) - Critical Outcome Technologies Inc. ("COTI" or the "Company") (COT:CA) (COTQF) announced today that the European Patent Office has granted the Company European Patent No. 2121681 for its lead cancer drug candidate, COTI-2. This patent covers the composition of matter of COTI-2, the Company's small molecule activator of misfolded mutant p53 protein. Issuance of this European patent provides the Company with additional protection and licensing opportunities for the COTI-2 franchise in European markets.

"COTI-2's overall patent protection continues to strengthen as we prepare for our upcoming Phase 1 clinical trial in gynecologic cancers," said Dr. Wayne Danter, President and CEO of COTI. "With nine patents now issued for COTI-2 and several more pending worldwide, we have a growing intellectual property position protecting COTI-2 that supports our efforts to maximize future commercial licensing opportunities."

European Patent No. 2121681 covers a number of chemical structures in the COTI-2 family of compounds, pharmaceutical preparations containing COTI-2, methods of manufacturing the compounds and use of the compounds in the treatment of cancer in the European market until January 2028. This subject matter has previously been protected with patents in the U.S., Japan and Canada.

About Critical Outcome Technologies Inc.

COTI is a biopharmaceutical company using machine learning to rapidly develop targeted therapies. COTI's proprietary artificial intelligence platform, CHEMSAS®, utilizes a series of predictive computer models to identify compounds with a high probability of being successfully developed from disease specific drug discovery through chemical optimization and preclinical testing. These compounds are targeted for a variety of diseases, particularly those for which current treatments are either lacking or ineffective.

Follow @CriticalOutcome on Twitter at http://twitter.com/CriticalOutcome

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