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Repros Jumps on Positive Drug Trials

By  +Follow September 17, 2013 8:01AM
Tickers Mentioned:

Shares in Texas pharma Repros Therapeutics, Inc. (RPRX) gapped up over 30 percent in early morning trading before settling into gains of just over 10 percent on heavy volume as the day wore on. The spike, driven by positive topline results from the most recent study on its drug Androxal® reported after close on Monday, pushed Repros stock to a new 52-week high.

Positive results for Androxal

Androxal is being developed for men of reproductive age with low testosterone due to secondary hypogonadism, which is also associated with obesity and could be among the most common causes of low testosterone. Repros reported that Andorxal met both co-primary endpoints in its second pivotal study, with 81 percent of subjects using the drug experiencing normalized testosterone and no 24-hour average testosterone levels outside of normal ranges. Androxal, which is in a class similar to Sanofi’s (SNY) Clomid®, could receive a strong share of the testosterone replacement therapy (TRT) market because it could also help preserve male fertility while being administered orally, making it significantly more convenient than testosterone replacement injections.  

Possible Sale

Brean Capital initiated coverage of Repros in July of this year, calling it a buy and setting a price target of $32. At the time, analyst Jonathan Aschoff said “Its lead compound Androxal is being evaluated in a Phase 3 program for secondary hypogonadism with results in 4Q13 and 2Q14, which in our view would be key investment catalysts, and we project Androxal launch in mid-2015.” Now, Brean is citing these positive results as a reason for optimism, as well as reports that management may have interest in selling the company. Brean estimated the sell-price potentially reaching $40 a share, in the event that the sale goes down.

In addition to Andorxal, Repros currently has female reproductive drug Proellex® in the pipeline, intended for use in uterine fibroids and endometriosis. “The vaginal formulation of Proellex (Proellex-V) will enter Phase 2b in 2H13 for uterine fibroids with an NDA submission expected in 2016. All compounds are protected by U.S. patents," said Aschoff in July.

DISCLOSURE: The views and opinions expressed in this article are those of the authors, and do not represent the views of equities.com. Readers should not consider statements made by the author as formal recommendations and should consult their financial advisor before making any investment decisions.

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Results for RPRX
2 Sep 14 08:59:05
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Sleek Money
2 Sep 14 04:38:44
Repros Therapeutics’s Positive Rating Reiterated at Ascendiant Capital Markets $RPRX http://t.co/R9CwU2EWCy
Market Updates
2 Sep 14 03:45:00
$RPRX: REPROS THERAPEUTICS INC. Files SEC form 8-K, Regulation FD Disclosure http://t.co/E1vtm6FikQ http://t.co/fVJBsayoGa
2 Sep 14 03:04:47
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1 Sep 14 08:45:16
$RPRX: Why Repros Therapeutics (RPRX) Stock Is Surging Today http://t.co/ruv6qfGPDn http://t.co/ZEXzxFEupb
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31 Aug 14 21:44:59
$RPRX: Why Repros Therapeutics (RPRX) Stock Is Surging Today http://t.co/S8cLTrR302 http://t.co/RosoBxRKeZ
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30 Aug 14 05:44:59
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29 Aug 14 12:45:06
$RPRX: REPROS THERAPEUTICS INC. Files SEC form 8-K, Regulation FD Disclosure http://t.co/iUqGpf5kjx http://t.co/E1aFVyr1WZ
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29 Aug 14 12:35:50
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29 Aug 14 10:45:07
$RPRX: Repros Therapeutics reaches enrollment goal in second Androxal study http://t.co/ZN60w4udse http://t.co/yORjr8iKEX
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29 Aug 14 08:49:20
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Stock News Headlines
29 Aug 14 08:45:06
$RPRX: Repros Therapeutics (RPRX) Reports Positive Top Line Data in Androxal Studies http://t.co/5IftmebGeh http://t.co/GHu9lE225i
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29 Aug 14 08:33:01
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29 Aug 14 08:26:41
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By  +Follow September 17, 2013 8:01AM



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